Periodic Congress



Upcoming sessions


December 2021

Add to calendar

Wednesday 1 December 2021 – 17:00 – 19:00

Session 12 Advances and late breaking abstracts
  Moderators: Marco Gattorno (IT), Helen Lachmann (UK), Dan Kastner (US)
17:00 Overview of genetic cause of SAID - 2021 update
Ivona Aksentijevich (US)
17:20 O13 - Disease flares in CANDLE/PRAAS with dose reductions of baricitinib
Kader Cetin Gedik (US)
17:30 O14 - Systemic juvenile idiopathic arthritis associated lung disease in Europe
Claudia Bracaglia (IT)
17:40 O15 - Tocilizumab for VEXAS syndrome with relapsing polychondritis: Extension study
Yosuke Kunishita (JP)
17:50 O16 - Genetic and immunologic characterization of male and female patients with nemo-deleted Exon 5 autoinflammatory syndrome
Adriana A. de Jesus (US)
18:00 O17 - Existing transition practices for autoinflammatory diseases across Europe
M. Israni (UK)
18:10 O18 - Covid-19 infection and vaccination in patients with autoinflammatory diseases on biologics
Claire J Peet (UK)
18:20 Discussion




Past sessions available on-demand


May 2021
Register & Watch recording

Wednesday 26 May 2021 – 17:00 – 19:00

  Moderators: Marco Gattorno (IT), Helen Lachmann (UK)
Opening session: Opening Lecture
17:00 The expansion of the autoinflammatory universe
Dan Kastner (US)
Session 1 (auto)inflammatory consequences of actin dysregulation
17:20 Clinical features of (auto)inflammatory consequences of actin dysregulation
Paul Brogan (UK)
17:40 Mechanistic insights: autoinflammation and actin
Kaan Boztug (AT)
18:00 O01 - The possible effect of MIR-30E-3P which targets IL-1β in the pathogenesis of systemic autoinflammatory diseases
Tayfun Hi̇lmi̇ Akbaba (TR)
18:10  O02 - Number of episodes can be used as a disease activity measure in Familial Mediterranean Fever
David Piskin (CA)
18:20 Discussion


June 2021
Register & Watch recording

Wednesday 9 June 2021 – 17:00 – 19:00

Session 2 Diagnosis and management of non-genetically determined recurrent fevers
  Moderators: Amita Arggawal (IN), Philip Hashkes (IL)

State-of-the art lecture: Everything you need to know about PFAPA in 2021
Kaplana Manthiram (US)

17:20 Round table discussion:  How do I manage patients with recurrent fevers of unknown origin  (PFAPA, SURF, etc)
Michael Hofer (CH): How do I make diagnosis?
Lori Broderick (US): Is SURF a clinical entity?
Sophie Georgin-Lavialle (FR): Undefined recurrent fevers in adults
Saskya Angevare (NL) and Karen Durrant (US): Patients perspectives
View full programme Familial Mediterranean Fever: Contextualizing anti IL-1 Therapy to Achieve and Sustain Therapy Goals

Welcome and opening remarks
The roadmap to optimizing FMF outcomes with anti IL-1 therpay?
Marco Gattorno (IT)

  FMF treatment goals
Meeting and sustaining patient need
Eldad Ben-Chetrit (IL)
  What are the treatment expectations for a patient with FMF
Considering a holistic approach to achieve quality of life goals?
Veronique Hentgen (FR)
  Anti IL-1 therapy treatment paradigms
Marco Gattorno (IL)
  Live panel discussion: Summing it up


June 2021

Register & Watch recording

Wednesday 23 June 2021 – 17:00 – 19:00

Session 3 The clinical presentation and treatment of MIS-C around the world
  Moderators: Jasmine Kuemmerle-Deschner (DE), Joost Frenkel (NL)
17:00 The kaleidoscope of MIS-C
Angelo Ravelli (IT)
17:20 O03 - Long-term cardiac outcome in patients with multisystem inflammatory syndrome in children (MIS-C)
Andrea Taddio (IT)
17:30 Panel Discussion MIS-C: News from the World

Isabelle Koné-Paut (FR): MIS-C in Europe
Maria Cecilia Poli Harlowe (CL): MIS-C in South America
Kate Webb (ZA): MIS-C in Africa
Suma Balan (IN): MIS-C in India

Fatma Dedeoglu (US): MIS-C in North America


July 2021
Register & Watch recording

Wednesday 7 July 2021 – 17:00 – 19:00

Session 4 Pulmonary involvement in autoinflammatory diseases (SAIDs)
  Moderators: Seza Ozen (TR), Paul Brogan (UK)
17:00 Interferonopathies
Raphaela Goldbach-Mansky (US)
17:20 Systemic Onset Juvenile Idiopathic Artiritis
Bas Vastert (NL)
17:40 Discussion
NOVARTIS Symposium Novel Approaches to Personalized Patient Care in Still’s Disease

Welcome and Introduction
Carine Wouters, MD, PhD (BE)


The Transition from Paediatric to Adult Care: What Can We Learn From Experience with JIA? 
Carine Wouters, MD, PhD (BE)

18:20 Digital Tools for the Management of Rare Autoinflammatory Diseases 
Johannes Knitza, MD, MHBA (DE)
18:35 Biomarkers and Their Sense or Nonsense in the Management of Still’s Disease
Lorenzo Dagna, PhD (IT)
18:50 “Ask the Faculty” and Take-Home Messages 
Carine Wouters, MD, PhD (BE), Lorenzo Dagna, MD (IT) and Johannes Knitza, MD, MHBA (DE)


July 2021

Register & Watch recording

Wednesday 21 July 2021 – 17:00 – 19:00

Session 5 Autoinflammation in COVID-19
  Moderators: Stefano Volpi (IT), Marco Gattorno (IT)
17:00 Inflammatory cell death (pyroptosis) in SARS-CoV-2 infection
Judy Lieberman (US)
17:20 Genetic and immune determinants of response to SARS-CoV-2
Luigi Notarangelo (US)
17:40 The pathogenesis and clinical spectrum of MIS-C
Lauren Henderson (US)
18:00 O04 - SARS-COV2 ORF3A protein drives inflammation in COVID-19 through NLRP3 inflammasome activation
Stefano Volpi (IT)
18:10 Discussion
NOVARTIS Meet the Expert Meet the experts: Stills’ disease and its mimics
18:30 New data on biomarkers in AOSD - does it help for diagnosis and prognosis?
Eugen Feist, Germany
18:40 Still’s disease – overlays to monogenetic diseases?
Sinisa Savic, United Kingdom
18:50 Q&A


Register & Watch recording

Wednesday 22 September 2021 – 17:00 – 19:00

Session 7 Metabolism and Autoinflammation
  Moderators: Scott Canna (US)
17:00 The clinical spectrum of LACC1-disorders
Sulaiman Al-Mayouf (SA)
17:20 Famin/LACC1 
Alexandre Belot (FR)
17:40 IL-1 blockade in heart disease
Antonio Abbate (US)
18:00 O07 - Short-term follow-up results of children with Familial Mediterranean Fever after cessation of Canakinumab
Hafize Emine Sönmez (TR)

O08 - Traditional laboratory parameters and new biomarkers in Macrophage Activation Syndrome (MAS) and Secondary Hemophagocytic Lymphohistiocytosis (SHLH)
Arianna De Matteis (IT)

18:20 Discussion


October 2021
Register & Watch recording

Wednesday 6 October 2021 – 17:00 – 19:00

Session 8 Enzymes bridging the gap between genes, autoimmunity and inflammation
  Moderators: Marie-Louise Frémond (FR), Stefano Volpi (IT)
17:00 A clinical overview on TREX1 and DNASE2
Yannick Crow (UK)
17:20 Bridging monogenic diseases with autoimmunity
Boris Reizis (US)
17:40 Linking plasma DNA profiles with nucleases
Dennis Lo (HK)
18:00 O09 - Dissecting netosis in adenosine deaminase 2 deficiency (DADA2) patients
Francesca Schena (IT)
18:20 Discussion


Register & Watch recording

Wednesday 20 October 2021 – 17:00 – 19:00

Session 9 Approaches to genomic mutation detection in SAID
  Moderator: Isabelle Touitou (FR)
17:00 Genotype-driven, phenotype-neutral approach; detection of VEXAS syndrome
David Beck (US)
17:20 Phenotype-driven genomic diagnostics; LIRICAL
Peter Robinson (US)
17:40 Human phenotype ontology and its importance in autoinflammation
Marielle van Gijn (NL)
18:00 O10  - Next generation sequencing based multiplex long-range PCR for routine genotyping of autoinflammatory disorders
Erkan Demirkaya (CA)
18:10 Discussion
November 2021

Wednesday 3 November 2021 – 17:00 – 19:00

Session 10 New therapies in autoinflammation
  Moderator: Maria Cecilia Poli Harlowe (US)
17:00 General lecture: an update on treatment
Helen Lachmann (UK)
17:20 Immunometabolism Meets inflammation: therapeutic possibilities
Luke O'Neill (IE)
17:40 Blocking the IFN pathway
Andrea Ablasser (CH)
18:00 O11 - Gene therapy for IL-1-mediated systemic autoinflammatory diseases
Mariasilvia Colantuoni (IT)
18:10 O12 - Application of systems biology-based in silico tools to optimize treatment strategy in Still’s disease
Mireia Coma (ES)
18:20 Discussion

Wednesday 17 November 2021 – 17:00 – 19:00

Session 11 New guidelines for autoinflammatory diseases
  Moderators: Raphaela Goldbach-Mansky (US), Erkan Demirkaya (CA), Fabrizio De Benedetti (IT)
17:00 Interferonopathies
Kader C. Gedik, Micol Romano, Lovro Lamot
17:30 IL-1 mediated diseases
Micol Romano, Zehra S. Arici, David Piskin
18:00 HLH-MAS
Scott Canna, Bita Shakoory, Rebecca Marsh
18:30 Discussion

About us

IssaidThe International Society of Systemic Auto-Inflammatory Diseases (ISSAID) raise awareness, catalyse basic research and promote scientific and clinical knowledge on all aspects of systemic auto-inflammatory diseases.

Contact Information

ISSAID 2021 c/o MCI Geneva
9, rue du Pré-Bouvier
1242, Satigny, Geneva


Official Website: